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Showing posts with label Differential Diagnosis. Show all posts
Showing posts with label Differential Diagnosis. Show all posts

Thursday, March 27, 2014

Differential Diagnosis for convulsions (fits) for a child

This post mainly consist differential diagnosis and how it can differentiate

Meningitis / Encephalitis

  • Fever,
  • Drowsines,
  • Irritabilit,
  • Photo phobi,
  • History of upper respiratory track infection or Ear discharge
  • Purpuric skin rashers (Neisseria meningitidis)
  • Neck stiffness
  • Skin infection (Staphylococcus aureus)

Tuberculous Meningitis

  • Contact history of Tuberculosis
  • BCG scar
  • Mantoux test

Cerebral malaria

  • Travel to malaria endemic erea
  • Fever with chills and rigours

Febrile convulsions 

  A febrile convulsion is a seizure that occur between the age of 3 months to 6 years with fever that is not result of central nervous system infection or any metabolic imbalance, and that occur in the absence of a history of prior afebrile seizures.
  • Benign
  • Occur with fever
  • Age 6 month to 5 years
  • Less postictal drowsiness
  • Usually less than 15 min ( if more than it, It is a complex febrile convulsions.)

Difference of simple and complex febrile convulsions

Simple febrile convulsion

  • Less than 15 minutes (few seconds)
  • Primary generalized 
  • Usually tonic clonic
  •  Not recurrent within a 24 hour period
  • Chance of developing subsequent epilepsy is not increased. Same as all children (1- 2%). 

Complex febrile convulsion

  • Continue more than 15 minutes,
  • Focal,
  • Recurs within 24 hours,
  • Chance of developing subsequent epilepsy is increased. (4- 12%)

Epilepsy

  • Long postictal drowsiness
  • Past history of convulsions
  • Antyepileptic drug withdrawal
  • Neurocutaneous markers on skin

Neurocutaneous markers cafe au lait patches and neurofibroma
       pic.1 cafe au lait patches,(black arrows) neurofibroma (white)

Metabolic causes

  • Hypoglycemia
    • fasting, associated with sweating
  • Hyponatraemia
    • vomiting, diarrhea

Head trauma

Toxins and drugs